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Flomax Drug Interactions
Other alpha blockers, warfarin, or cimetidine can cause problems with combine with Flomax. These drug interactions could cause your blood pressure to become dangerously low or increase your risk of side effects. To ensure your safety, you may need to be monitored more closely when first starting Flomax, or your healthcare provider may change your medications altogether.
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Flomax® (tamsulosin hydrochloride) can potentially react with many medicines. Some of the drugs that may lead to Flomax interactions include:
- Other alpha blockers similar to Flomax, such as:
- Certain antibiotics or antifungals, such as:
- Clarithromycin (Biaxin®)
- Erythromycin (Ery-Tab®)
- Isoniazid (Nydrazid®)
- Itraconazole (Sporanox®)
- Ketoconazole (Nizoral®)
- Miconazole
- Telithromycin (Ketek®)
- Chlorpromazine
- Cimetidine (Tagamet®)
- Delavirdine (Rescriptor®)
- Diclofenac (Cataflam®, Voltaren®)
- Fluoxetine (Prozac®, Sarafem®)
- Imatinib (Gleevec®)
- Nefazodone (Serzone®)
- Nicardipine (Cardene®)
- Paroxetine (Paxil®, Paxil CR®)
- Pergolide (Permax®)
- Protease inhibitors, such as:
- Amprenavir (Agenerase®)
- Atazanavir (Reyataz®)
- Fosamprenavir (Lexiva®)
- Indinavir (Crixivan®)
- Nelfinavir (Viracept®)
- Ritonavir (Norvir®)
- Quinidine
- Quinine
- Ropinirole (Requip®)
- Terbinafine (Lamisil®)
- Warfarin (Coumadin®, Jantoven®).
Other medications that are similar to Flomax can interact with phosphodiesterase type 5 inhibitors (PDE5 inhibitors), including tadalafil (Cialis®, Adcirca®), vardenafil (Levitra®, Staxyn™), sildenafil citrate (Viagra®, Revatio®), and avanafil (Stendra™). Although Flomax does not seem to interact with these drugs, caution should be used when combining these medications (see Combining Levitra with Flomax).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD