Prostate Home > Precautions and Warnings With Cardura

Precautions and warnings with Cardura should be reviewed prior to taking the drug. For example, it may not be safe to take the medication during pregnancy. Possible side effects can include vertigo and fainting, and some drugs can interact negatively when taken when Cardura. Precautions and warnings with Cardura also extend to people who have liver disease or who are allergic to any component of the drug.

Cardura: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Cardura® (doxazosin mesylate) if you have:
  • Liver problems, including liver failure or cirrhosis
  • Any allergies, including allergies to foods, dyes, or preservatives.
Also let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
It's important to also tell your healthcare provider about all of the medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Warnings and Precautions With Cardura

Warnings and precautions to be aware of prior to taking Cardura include the following:
  • Cardura is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy. Because Cardura has not been studied in pregnant women, the full risks of using Cardura during pregnancy are not known (see Doxazosin and Pregnancy for more information).
  • It is not known if Cardura is passed through breast milk. Therefore, if you are breastfeeding or plan to start, talk with your healthcare provider about this.
  • Cardura can cause lightheadedness, dizziness, a spinning sensation (vertigo), and fainting, especially when standing up. These side effects are often caused by low blood pressure. These problems are more likely to occur after taking the very first dose of Cardura, any time the dose is increased, or when restarting Cardura after stopping it -- even if just for a few days. To decrease the chance of these problems, you should start at the lowest dose (1 mg daily), and the dose should be increased slowly. For the first 24 hours after starting or increasing Cardura, avoid situations that might be dangerous, such as driving or operating heavy machinery, especially if you are having symptoms of low blood pressure. Tell your healthcare provider if you are having trouble with any of these symptoms. Your blood pressure should be carefully monitored when starting or increasing Cardura.
  • In rare cases, Cardura has been reported to cause priapism, a painful erection of the penis that does not go away. Even though it may seem embarrassing, you need to seek medical attention right away if you have priapism, as it made lead to permanent damage to the penis (see Doxazosin Sexual Side Effects for more information).
  • Cardura has been reported to cause intraoperative floppy iris syndrome, a problem with the eyes that can occur during cataract surgery. This problem has occurred in people who were currently taking Cardura and in people who had stopped taking the drug. Before having eye surgery, be sure to tell your healthcare provider if you are or have been on Cardura.
  • Before you start taking Cardura, your healthcare provider should make sure that your enlarged prostate symptoms are not caused by another condition, such as prostate cancer or bladder problems.
  • Because the liver helps to clear Cardura from the body, you should talk with your healthcare provider before taking Cardura if you have liver problems, including liver failure or cirrhosis.
  • Cardura can interact with certain medications (see Drug Interactions With Cardura).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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