Uroxatral is a prescription drug licensed for the treatment of benign prostatic hyperplasia (BPH), a condition in which the prostate becomes enlarged. This medication works by relaxing the muscles of the prostate and the neck of the bladder. Uroxatral comes as a 10 mg tablet and is generally taken once a day after a meal. Potential side effects may include dizziness, headaches, and fatigue.
What Is Uroxatral?
Uroxatral® (alfuzosin hydrochloride) is a prescription medication approved to treat the signs and symptoms of an enlarged prostate (known medically as benign prostatic hyperplasia, or BPH).
Uroxatral is part of a class of drugs known as alpha blockers. In particular, it works by blocking alpha-1 receptors. Alpha-1 receptors are found in several places of the body, including the prostate gland.
When used for the treatment of BPH, alpha-1 blockers help to relax the muscles of the prostate and the bladder neck (where urine leaves the bladder). Uroxatral does not shrink the prostate, as some other BPH medications do. However, by relaxing the muscles of the prostate and bladder, Uroxatral helps to quickly relieve BPH symptoms. While this medication can help with symptoms, it is not a cure for BPH.
Effectiveness of Uroxatral
Uroxatral has been thoroughly evaluated in several different clinical studies. These studies showed that Uroxatral decreased BPH symptoms (such as frequent urination and a weak stream) and increased urine flow rate more than a placebo (a "sugar pill" that does not contain any active ingredients).
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Uroxatral [package insert]. Bridgewater, NJ: sanofi-aventis U.S. LLC;2008 February.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed August 24, 2012.
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