Proscar
® (
finasteride) is a prescription medicine that has been licensed as treatment for an
enlarged prostate. An enlarged prostate is also known medically as benign prostatic hyperplasia, benign prostatic hypertrophy, or
BPH.
(Click Proscar Uses for more information on what Proscar is used for, including possible off-label uses.)
Proscar is manufactured by Merck & Co, Inc.
Generic Proscar is made by several manufacturers.
Proscar works by blocking the conversion of testosterone into DHT (dihydrotestosterone), which decreases the amount of DHT in the body. Since DHT is important for enlargement of the prostate, using Proscar to decrease DHT levels can treat an enlarged prostate. In most men, Proscar can help shrink the enlarged prostate, helping to relieve their
enlarged prostate symptoms.
There have been several studies looking at how well Proscar treats an enlarged prostate. In particular, there has been one very large study that studied several of the effects of Proscar for men with BPH, with the following results:
Symptoms of BPH
The men in this study were asked to rate the following symptoms of
BPH:
- Decreased size and force of urine stream
- Feeling of incomplete bladder emptying when urinating
- Delayed or interrupted urination
- Having to get up to urinate frequently during the night
- Having to urinate frequently during the day
- Needing to strain or push the flow of urine.
The men who took Proscar had significant improvement in their BPH symptoms compared to the men who did not take Proscar. While some patients saw improvement right away, in general, it took about six months to see the improvement for most men. This improvement lasted throughout the entire study period (four years).
Acute Urinary Retention
This study also looked at how many men had acute urinary retention. If an
enlarged prostate is very severe, a man may not be able to urinate at all. This is known medically as acute urinary retention and usually requires catheterization (inserting a small tube through the penis into the bladder in order to empty the urine). Of the men who took Proscar, 2.8 percent experienced acute urinary retention that required catheterization, compared to 6.6 percent of men who did not take Proscar.
Surgery
In this study, 4.6 percent of men who took Proscar needed to have BPH surgery, while 10.1 percent of men who did not take Proscar needed to have surgery.
Urine Flow
Men who took Proscar also had an improvement in the rate of urine flow. This increased flow rate was seen as early as the fourth month after starting Proscar and continued throughout the entire study.
When and How to Take Proscar
Some general considerations for when and how to take Proscar include:
- Proscar comes in tablet form. It is taken by mouth once daily.
- It may take as long as six months before results can be seen with Proscar.
- Proscar can be taken with or without food.
- Proscar should be taken at the same time each day to maintain an even level of the drug in your blood.
- For Proscar to work properly, it must be taken as prescribed. Proscar will not work if you stop taking it.
As with any medication, do not adjust your Proscar dose unless your healthcare provider specifically instructs you to do so.
As with any medicine, there are possible side effects with Proscar. However, not everyone who takes the medicine will experience side effects. In fact, most people tolerate Proscar well. When Proscar side effects do occur, they are often minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
The most common side effects of Proscar include:
(Click Proscar Side Effects to learn about the specific side effects of Proscar, including serious side effects to look out for.)
You can also read about other possible side effects by clicking on the following eMedTV links:
Drug Interactions With Proscar
There are no known drug interactions with Proscar.
Proscar: What Should I Tell My Healthcare Provider?
You should talk with your healthcare provider before taking Proscar if you have:
- Liver disease or liver failure, including cirrhosis
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
Tell your healthcare provider about all other medicines you may currently be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
In studies, large doses of Proscar did not cause any overdose symptoms.
If you happen to overdose on Proscar, or if you are a pregnant woman who has taken any amount of Proscar, seek medical attention immediately.
Proscar should be stored at room temperature away from moisture or heat. Proscar tablets should be kept in an airtight container. Because Proscar is so dangerous for pregnant women, women should not touch broken or crushed Proscar tablets if they are pregnant or may be pregnant.
Keep Proscar and all medications out of the reach of children.
Proscar: What Should I Do If I Miss a Dose?
If you do not take your Proscar as scheduled, take your next dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose of Proscar.
Proscar tablets are available in one strength -- Proscar 5 mg tablets.
Propecia®, a medication used for treating male pattern baldness, contains the same active ingredient as Proscar --
finasteride. However, Propecia is available only in 1 mg tablets, which is not the correct dose for treating
BPH (see Proscar and Hair Loss for more information).
(Click on Propecia and Proscar for more information about the differences between Proscar and Propecia.)
Generic Proscar is currently licensed for sale.
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